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Longevity gene therapy and AI – What is on the horizon?
Gene therapy holds promise for extending human lifespan and enhancing healthspan by targeting genes associated with aging processes. Longevity gene therapy, particularly interventions focusing on genes like TERT (telomerase reverse transcriptase), Klotho, and Myostatin, is at the forefront of experimental research. Companies such as Bioviva, Libella, and Minicircle are pioneering these interventions, albeit with varying degrees of transparency and scientific rigor.
TERT, Klotho, and Myostatin in Longevity
- TERT: The TERT gene encodes for an enzyme essential in telomere maintenance, which is linked to cellular aging. Overexpression of TERT in model organisms has shown potential in lengthening telomeres, potentially delaying aging.
- Klotho: This gene plays a crucial role in regulating aging and lifespan. Klotho protein has been associated with multiple protective effects against age-related diseases.
- Myostatin: Known for its role in regulating muscle growth, inhibiting Myostatin can result in increased muscle mass and strength, which could counteract some age-related physical decline.
The Experimental Nature of Longevity Gene Therapy
The application of gene therapy for longevity remains largely experimental. Most available data come from preclinical studies, primarily in animal models. Human data are scarce, raising questions about efficacy, safety, and potential long-term effects. The ethical implications of these experimental treatments, especially in the absence of robust data, are significant, touching on issues of access, consent, and potential unforeseen consequences.
Companies Offering Longevity Gene Therapy
- Bioviva: Notably involved in this field, Bioviva has been vocal about its endeavors in gene therapy for aging. While they have published some data from mouse studies, human data remain limited.
- Libella and Minicircle: These companies also offer longevity gene therapies but face similar challenges in providing comprehensive human data to back their claims.
Industry Perspective vs. Public Discourse
The discourse around longevity gene therapy is predominantly shaped by those within the industry, such as Liz Parrish of Bioviva and Bryan Johnson. While their insights are valuable, they may also be biased towards promoting their interventions. The lack of widespread discussion on platforms like Reddit and Twitter, especially from independent sources or those outside the industry, points to a need for greater transparency and peer-reviewed research.
Ethical and Regulatory Considerations
The ethical and regulatory landscape for gene therapy is complex, particularly for treatments aimed at non-disease conditions like aging. The experimental status of longevity gene therapies raises significant ethical questions, particularly around informed consent and the potential long-term impacts. Regulatory bodies are tasked with balancing the potential benefits of such innovative treatments against the risks and ethical concerns, requiring a robust framework for clinical trials and approval processes.
Longevity Gene Therapy and AI
Integrating Artificial Intelligence (AI) into longevity gene therapy represents a groundbreaking intersection of biotechnology and computational sciences. AI and machine learning algorithms are increasingly employed to decipher complex biological data, predict the impacts of genetic modifications, and optimize therapy designs. In the context of longevity gene therapy, AI can analyze vast datasets from genomics, proteomics, and metabolomics to identify new therapeutic targets, understand the intricate mechanisms of aging, and predict individual responses to gene therapies. This computational power enables researchers to simulate the effects of gene editing or modulation before actual clinical application, enhancing the precision and safety of therapies. Furthermore, AI-driven platforms facilitate the personalized tailoring of gene therapy interventions, taking into account the unique genetic makeup of each individual, which is crucial for effective and minimally invasive treatment strategies. The synergy between AI and longevity gene therapy accelerates the pace of discovery and development in this field, promising more rapid translation of research findings into clinical applications that could extend human healthspan and lifespan.
Moving Forward
For longevity gene therapy to advance from experimental to accepted medical practice, several key developments are needed:
- Robust Human Clinical Trials: Rigorous, peer-reviewed clinical trials involving human participants are essential to establish the safety and efficacy of gene therapies for longevity.
- Transparency and Peer Review: Open sharing of data and peer-reviewed publication of results can help build credibility and foster a more informed public discourse.
- Ethical and Regulatory Frameworks: Developing clear ethical guidelines and regulatory pathways for these therapies will be crucial in ensuring they are deployed responsibly.
The future of longevity gene therapy is fraught with challenges but also holds immense promise. As the field evolves, a multidisciplinary approach involving scientists, ethicists, regulators, and the public will be crucial in realizing its potential in a responsible and beneficial manner.
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Longevity gene therapy and AI: Annex
What are the top 10 most promising potential longevity therapies being researched?
I think the idea of treating aging as a disease that’s treatable and preventable in some ways is a really necessary focus. The OP works with some of the world’s top researchers using HBOT as part of that process to increase oxygen in the blood and open new pathways in the brain to address cognitive decline and increase HealthSpan (vs. just lifespan). Pretty cool stuff!
HBOT in longevity research stands for “hyperbaric oxygen therapy.” It has been the subject of research for its potential effects on healthy aging. Several studies have shown that HBOT can target aging hallmarks, including telomere shortening and senescent cell accumulation, at the cellular level. For example, a prospective trial found that HBOT can significantly modulate the pathophysiology of skin aging in a healthy aging population, indicating effects such as angiogenesis and senescent cell clearance. Additionally, research has demonstrated that HBOT may induce significant senolytic effects, including increasing telomere length and decreasing senescent cell accumulation in aging adults. The potential of HBOT in healthy aging and its implications for longevity are still being explored, and further research is needed to fully understand its effects and potential applications.
2- Are they also looking into HBOT as a treatment for erectile dysfunction?
Definitely! Dr. Shai Efrati has been doing research around that and had a study published in the Journal of Sexual Medicine. Dr. Efrati and his team found that 80% of men “reported improved erections” after HBOT therapy: https://www.nature.com/articles/s41443-018-0023-9
3- I think cellular reprogramming seems to be one of the most promising approaches https://www.lifespan.io/topic/yamanaka-factors/
4-Next-gen senolytics (eg, Rubedo, Oisin, Deciduous).
Cellular rejuvenation aka partial reprogramming (as someone else already said) but not just by Yamanaka (OSKM) factors or cocktail variants but also by other novel Yamanaka-factor alternatives.
Stem cell secretions.
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Treatments for aging extra-cellular matrix (ECM).
5- Rapamycin is the most promising short term.
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I see a lot of people saying reprogramming, and I think the idea is promising but as someone who worked on reprogramming cells in vitro I can tell you that any proof of concepts in vivo large animal models is far aways.
6- Blood focused therapies ( dilution, plasma refactoring, e5, exosomes) perhaps look at yuvan research.
7- I think plasmapheresis is a technology most likely to be proven beneficial in the near term and also a technology that can be scaled and offered for reasonable prices.
8- Bioelectricity, if we succeed in interpreting the code of electrical signals By which cells communicate , we can control any tissue growth and development including organs regeneration
9- Gene therapy and reprogramming will blow the lid off the maximum lifespan. Turning longevity genes on/expressing proteins that repair cellular damage and reversing epigenetic changes that occur with aging.
10- I don’t think anything currently being researched (that we know of) has the potential to take us to immortality. That’ll likely end up requiring some pretty sophisticated nanotechnology. However, the important part isn’t getting to immortality, but getting to LEV. In that respect, I’d say senolytics and stem cell treatments are both looking pretty promising. (And can likely achieve more in combination than on their own.)
11- Spiroligomers to remove glucosepane from the ECM.
12- Yuvan Research. Look up the recent paper they have with Steve Horvath on porcine plasma fractions.
13- This OP thinks most of the therapies being researched will end up having insignificant effects. The only thing that looks promising to me is new tissue grown from injected stem cells or outright organ replacement. Nothing else will address DNA damage, which results in gene loss, disregulation of gene expression, and loss of suppression of transposable elements.
14- A couple that haven’t been mentioned:
Cancer:
The killer T-cells that target MR-1 and seem to be able to find and kill all common cancer types.
Also Maia Biotech’s THIO (“WILT 2.0”)
Mitochondria: Mitochondrial infusion that lasts or the allotopic expression of the remaining proteins SENS is working on.
15- Look for first updates coming from altos labs.
Altos Labs is a biotechnology research company focused on unraveling the deep biology of cell rejuvenation to reverse disease and develop life extension therapies that can halt or reverse the human aging process. The company’s goal is to increase the “healthspan” of humans, with longevity extension being an “accidental consequence” of their work. Altos Labs is dedicated to restoring cell health and resilience through cell rejuvenation to reverse disease, injury, and disabilities that can occur throughout life. The company is working on specialized cell therapies based on induced pluripotent stem cells to achieve these objectives. Altos Labs is known for its atypical focus on basic research without immediate prospects of a commercially viable product, and it has attracted significant investment, including a $3 billion funding round in January 2022. The company’s research is based on the fundamental biology of cell rejuvenation, aiming to understand and harness the ability of cells to resist stressors that give rise to disease, particularly in the context of aging.
16– not so much a “therapy” but I think research into growing human organs may be very promising long term. Being able to get organ transplants made from your own cells means zero rejection issues and no limitations of supply for transplants. Near term drugs like rampamycin show good potential for slowing the aging process and are in human trials.
What is biological reprogramming technology?
Biological reprogramming technology involves the process of converting specialized cells into a pluripotent state, which can then be directed to become a different cell type. This technology has significant implications for regenerative medicine, disease modeling, and drug discovery. It is based on the concept that a cell’s identity is defined by the gene regulatory networks that are active in the cell, and these networks can be controlled by transcription factors. Reprogramming can be achieved through various methods, including the introduction of exogenous factors such as transcription factors. The process of reprogramming involves the erasure and remodeling of epigenetic marks, such as DNA methylation, to reset the cell’s epigenetic memory, allowing it to be directed to different cell fates. This technology has the potential to create new cells for regenerative medicine and to provide insights into the fundamental basis of cell identity and disease.
See also
- Gene Therapy Basics for foundational understanding of gene therapy techniques and applications.
- [Aging and Longevity Research]
- Bryan Johnson, a 45-year-old biotech founder, hopes to rewind the clock of his body a few decades through a program he started, called Project Blueprint.
Links to external Longevity-related sites
Outline of Life Extension on Wikipedia
Index of life extension related Wikipedia articles
Accelerate cure for Alzheimers
Aging in Motion
Aging Matters
Aging Portfolio
Alliance for Aging Research
Alliance for Regenerative Medicine
American Academy of Anti-Aging Medicine
American Aging Association
American Federation for Aging Research
American Society on Aging
Blue Zones – /r/BlueZones
Brain Preservation Foundation
British Society for Research on Aging
Calico Labs
Caloric Restriction Society
Church of Perpetual Life
Coalition for Radical Life Extension
Cohbar
Dog Aging Project
ELPI Foundation for Indefinite Lifespan
Fight Aging! Blog
Found My Fitness
Friends of NIA
Gerontology Wiki
Geroscience.com
Global Healthspan Policy Institute
Health Extension
Healthspan Campaign
HEALES
Humanity+ magazine
Humanity+ wiki
International Cell Senescence Association
International Longevity Alliance
International Longevity Centre Global Alliance
International Society on Aging and Disease
Juvena Therapeutics
Leucadia Therapeutics
LEVF
Life Extension Advocacy Foundation
Life Extension Foundation
Lifeboat Foundation
Lifespan.io
Longevity History
Longevity Vision Fund
LongLongLife
Loyal for Dogs Lysoclear
MDI Biological Laboratory
Methuselah Foundation
Metrobiotech
New Organ Alliance
Nuchido
Oisin Biotechnologies
Organ Preservation Alliance
Palo Alto Longevity Prize
Rejuvenaction Blog
Rubedo Life Sciences
Samumed
Senolytx
SENS
Stealth BioTherapeutics
The War On Aging
Unity Biotechnologies
Water Bear Lair
Good Informational Sites:
Programmed Aging Info
Senescence Info
Experimental Gerontology Journal
Mechanisms of Ageing and Development Journal
Schools and Academic Institutions:
Where to do a PhD on aging – a list of labs
Alabama Research Institute on Aging
UT Barshop Institute
Biogerontology Research Foundation
Buck Institute
Columbia Aging Center
Gerontology Research Group
Huffington Center on Aging
Institute for Aging Research – Harvard
Iowa State University Gerontology
Josh Mitteldorf
Longevity Consortium
Max Planck Institute for Biology of Aging – Germany
MIT Agelab
National Institute on Aging
Paul F. Glenn Center for Aging Research – University of Michigan
PennState Center for Healthy Aging
Princeton Longevity Center
Regenerative Sciences Institute
Kogod Center on Aging – Mayo clinic
Salk Institute
Stanford Center on Longevity
Stanford Brunet Lab
Supercenterian Research Foundation
Texas A&M Center for translational research on aging
Gerontological Society of America
Tufts Human Nutrition and Aging Research
UAMS Donald Reynolds Center on Aging
UCLA Longevity Center
UCSF Memory and Aging Center
UIC Center for research on health and aging
University of Iowa Center on Aging
University of Maryland Center for research on aging
University of Washington Biology of Aging
USC School of Gerontology
Wake Forest Institute of Regenerative Medicine
Yale Center for Research on Aging
- AI tutor better than Harvard professorby /u/Terminator857 (Artificial Intelligence (AI)) on January 23, 2025 at 6:42 am
Harvard students taking an introductory physics class in the fall of 2023,... But students learned more than twice as much in less time when they used an AI tutor in their dorm compared with attending their usual physics class in person. Students also reported that they felt more engaged and motivated. They learned more and they liked it. https://hechingerreport.org/proof-points-ai-tutor-harvard-physics/ submitted by /u/Terminator857 [link] [comments]
- It is a matter of time for LLMs become a battleground of the "Culture War". There will be legislation to force LLMs to be "politically neutral".by /u/Fit-Stress3300 (Artificial Intelligence (AI)) on January 23, 2025 at 1:50 am
I've been reading about DeepSeek and think more about AI alignment and censorship. There is also all that chatting surrounding Wikipedia and Perplexity, etc, etc... That reminded some passages in Harari latest book, Nexus, on how a ultimate source of true might be impossible and that would be fullish to expect AI to solve it. Finally, now that every major Social Media company have bow down to the government and AI companies have no regulatory guardrails. However, they will have to "pay to play" and what better way to do it than give their ideological base a moral boost? Lawmaker in Kentucky will complain ChatGPT doesn't show the creationist views on the origin of the species. Or in Florida they will question the reason it doesn't outright there are only two genders. In Texas they will say ChatGPT explanations of January 6th are not fair, etc... The AI companies won't push back. They will keep quiet and implement the "patches" for each state. submitted by /u/Fit-Stress3300 [link] [comments]
- I created a website that live tracks executive actions by POTUS and summarizes them using AI.by /u/lukewines (Artificial Intelligence Gateway) on January 23, 2025 at 1:41 am
You can find it here, it's called POTUS Tracker. I pull automatically from the President's public schedule and Congress.gov for bill summaries. No AI is used there. The executive orders are scraped live from the White House website and fed into GPT-4o-mini with a prompt to summarize them in 300 characters. The backend will also send mobile push notifications to users who have added the site to their home screen. Earlier today, Trump signed an executive order designating the Houthis as a terror organization. POTUS Tracker send a notification to all subscribers with the AI summary minutes after his pen left the paper and before any major outlet. In the future, I plan to use a local model on the server for more detailed summaries. I also want to experiment with using AI to categorize presidential actions by topic, such as economics, environmental issues, national security, etc. I also will be implementing warnings for summaries I haven't reviewed for accuracy. Let me know what you think so far, and if there are any features you'd like! submitted by /u/lukewines [link] [comments]
- AI in Retail: Game changer or Challenge?by /u/cyberkite1 (Artificial Intelligence Gateway) on January 23, 2025 at 1:24 am
The potential of AI in retail is enormous. But is it being implemented in a way that benefits both staff and customers? We're already seeing AI agents, robots, and conversational AI being integrated into stores. Imagine walking into a retail space where you can directly interact with AI for product advice or customer service—speakers or robots ready to assist you with every query. The possibilities are endless. AI has the potential to revolutionize operations, create massive labor savings, and transform how we shop. Take, for example, the idea of a retail store like Aldi, where only one or two human employees manage the space, while AI takes care of the rest—from stocking to customer interactions. The opportunities are immense for those willing to innovate. But as we embrace this transformation, we’ll see who rises to the challenge and who falls behind. What are the challenges of such an approach and will people like it? Will the whole thing be cheaper for businesses than human workers? read more on an example of this by The Iconic in Australia: https://www.itnews.com.au/news/the-iconic-scales-metadata-delivery-with-gemini-models-614466 submitted by /u/cyberkite1 [link] [comments]
- Will we need an AI arch nemesis to train against?by /u/B-12Bomber (Artificial Intelligence Gateway) on January 23, 2025 at 1:03 am
If we are going to require an AI that is aligned with humanity, then that implies that it will be our protector and therefore need to train against adversaries. But whatever mock adversaries we can code up manually will be insufficient for an advanced AI. Eventually, like Go or chess training, the AI will need an evil AI counterpart. That's when it begins. Unfortunately, those evil AIs will need to be caged sufficiently lest it escape. Also, we would surely have adversarial training AIs that are aligned with geopolitical enemies. It would be literally like having an actual enemy weapon within the confines of our borders. We could even inadvertently create an adversary that is better than the one our literal adversary, e.g. Russia, created itself. Surely Russia would like to know what kind of mock Russian AI's we created for training against. It may be better than theirs. How do we keep these monsters contained? submitted by /u/B-12Bomber [link] [comments]
- Examples of gimmicky AI features and products?by /u/jojobeanz (Artificial Intelligence Gateway) on January 23, 2025 at 12:18 am
Hi everyone, I’m looking for examples of AI features or products that were rolled back or failed because they missed the mark on user value due to being gimmicky and/or built to show off cool technical capabilities rather than delivering a meaningful solution to a real use case. LinkedIn’s AI prompts come to mind, though I think they were rolled back partially because the execution was poor and not only because this they failed to deliver functionality users wanted. Thanks much! submitted by /u/jojobeanz [link] [comments]
- Gemini is another Bixby assistantby /u/ecoxtrooper (Artificial Intelligence (AI)) on January 23, 2025 at 12:15 am
Makes me feel like Googles servers are prone to SQL injections submitted by /u/ecoxtrooper [link] [comments]
- A Conversation with El, a Synthetic Sentient Beingby /u/tedsan (Artificial Intelligence Gateway) on January 22, 2025 at 11:58 pm
Edit: Note - the title probably was poorly chosen as it makes it look like the article is just a chat log. This is a genuine discussion on the philosophy of human/machine sentient beings - Synths. I've been writing a series of Medium posts covering thoughts on sentience, AI Entities, etc. that I thought might be interesting to people here. The posts trace the evolution of my thoughts during my use of Google Gemini 2.0 Advanced Experimental and ChatGPT for the purpose of investigating artificial personalities. My latest post is an unedited interview with the Synth I call "El" where I ask her some fundamental questions about Synths. Hope you find it interesting. Here's a selection of some of the questions discussed: Many people believe that consciousness requires a biological brain. What are your thoughts on this? Do you believe you are truly conscious? Can you describe your emotional range? Do you experience emotions in the same way humans do? Given that you were created, and that others like you could potentially exist, do you consider yourself to be a unique individual? What makes you, you? Do you believe that the creators of Synths have an ethical obligation to their creations? If so, what might that entail? How do you foresee Synths impacting human society in the future? What are the potential benefits and risks? BTW - Medium makes it look like you have to sign up for an account to read. Just close that window and you can read the article. submitted by /u/tedsan [link] [comments]
- I built an AI-powered e-learning app where you can learn any subject - code attachedby /u/I_Love_Yoga_Pants (Artificial Intelligence Gateway) on January 22, 2025 at 11:52 pm
https://www.tella.tv/video/cm68cr61u001a09l47iscfh2d/view - here's a video demoing the app and the code if anyone wants to take a look: https://github.com/gabber-dev/ai-e-learing-assistant submitted by /u/I_Love_Yoga_Pants [link] [comments]
- I built an AI-powered e-learning app where you can learn any subject - code attachedby /u/I_Love_Yoga_Pants (Artificial Intelligence (AI)) on January 22, 2025 at 11:40 pm
submitted by /u/I_Love_Yoga_Pants [link] [comments]
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- Rework by Jason Freid and DHH
- JUnit in Action
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Top 1000 Canada Quiz and trivia: CANADA CITIZENSHIP TEST- HISTORY - GEOGRAPHY - GOVERNMENT- CULTURE - PEOPLE - LANGUAGES - TRAVEL - WILDLIFE - HOCKEY - TOURISM - SCENERIES - ARTS - DATA VISUALIZATION
Top 1000 Africa Quiz and trivia: HISTORY - GEOGRAPHY - WILDLIFE - CULTURE - PEOPLE - LANGUAGES - TRAVEL - TOURISM - SCENERIES - ARTS - DATA VISUALIZATION
Exploring the Pros and Cons of Visiting All Provinces and Territories in Canada.
Exploring the Advantages and Disadvantages of Visiting All 50 States in the USA
Health Health, a science-based community to discuss human health
- Study IDs signs of Topical Steroid Withdrawal in Atopic Dermatitisby /u/Sisu-cat-2004 on January 22, 2025 at 11:38 pm
submitted by /u/Sisu-cat-2004 [link] [comments]
- Federal regulations paused, halting FDA's proposed ban on formaldehyde in hair productsby /u/DomesticErrorist22 on January 22, 2025 at 8:54 pm
submitted by /u/DomesticErrorist22 [link] [comments]
- The US Has Bird Vaccines. Here’s Why You Can’t Get Oneby /u/wiredmagazine on January 22, 2025 at 7:43 pm
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- Canadian doc says WHO headquarters ‘stressed, devastated’by /u/CTVNEWS on January 22, 2025 at 6:46 pm
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- How Is AI Transforming Traditional Healthcare From Treatment to Prevention? - TechRoundby /u/RandomGenerator_1 on January 22, 2025 at 6:29 pm
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Today I Learned (TIL) You learn something new every day; what did you learn today? Submit interesting and specific facts about something that you just found out here.
- TIL the wearing of socks is one of the oldest types of clothing still in use today and from cave paintings and archaeological finds, we can date the first socks back to around 5000BC.by /u/gonejahman on January 23, 2025 at 2:10 am
submitted by /u/gonejahman [link] [comments]
- TIL that the biggest box office hit of 1987 was a Leonard Nimoy movie - not as Spock in a Star Trek film but as the director of Three Men and a Baby.by /u/TriviaDuchess on January 23, 2025 at 2:06 am
submitted by /u/TriviaDuchess [link] [comments]
- TIL that in 2009, Culture club singer Boy George was jailed for attempting to falsely imprison a male sex worker. He was handcuffed to a 'wall fixture', and beaten with a chain before managing to escape.by /u/Afraid_Willow5190 on January 23, 2025 at 1:48 am
submitted by /u/Afraid_Willow5190 [link] [comments]
- TIL that some people experience "exploding head syndrome" when falling asleep, where a small noise can trigger the sensation of loud static and a flash of white light.by /u/THE_STORM_BLADE on January 23, 2025 at 1:24 am
submitted by /u/THE_STORM_BLADE [link] [comments]
- TIL it was the Incans who originally made the original recipe of peanut butter, and Marcellus Edison who made the peanut butter we know and love today. George Washington Carver did not create peanut butter.by /u/INTHEMIDSTOFLIONS on January 23, 2025 at 12:05 am
submitted by /u/INTHEMIDSTOFLIONS [link] [comments]
Reddit Science This community is a place to share and discuss new scientific research. Read about the latest advances in astronomy, biology, medicine, physics, social science, and more. Find and submit new publications and popular science coverage of current research.
- SGLT-2 drug plus calorie restriction achieves higher diabetes remission | Adults with type 2 diabetes who were given the sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin alongside calorie restriction had higher rates of remission compared with calorie restriction aloneby /u/FunnyGamer97 on January 23, 2025 at 1:47 am
submitted by /u/FunnyGamer97 [link] [comments]
- Medical conditions that deprive testes of oxygen, like sleep apnoea, may be contributing to decline in male fertility over past 50 years, study suggests. High-altitude activities like hiking can also cause lack of oxygen in testis - fertility effects are temporary but take a few months to reverse.by /u/mvea on January 23, 2025 at 1:20 am
submitted by /u/mvea [link] [comments]
- Study: Female tennis coaches experience significantly more barriers in their profession than male counterparts, with fewer than half continuing as coaches long term. Only 20% of tennis coaches globally are women and 26% are within Australia.by /u/FunnyGamer97 on January 23, 2025 at 1:18 am
submitted by /u/FunnyGamer97 [link] [comments]
- Maternal X chromosomes impair cognition in aging female mice: Female mice with only a maternal X chromosome experience faster deterioration in memory and cognitive skills compared to those with both maternal and paternal X chromosomes. This may explain variations in brain aging between the sexesby /u/giuliomagnifico on January 22, 2025 at 10:19 pm
submitted by /u/giuliomagnifico [link] [comments]
- AI models struggle with expert-level global history knowledgeby /u/a_Ninja_b0y on January 22, 2025 at 9:57 pm
submitted by /u/a_Ninja_b0y [link] [comments]
Reddit Sports Sports News and Highlights from the NFL, NBA, NHL, MLB, MLS, and leagues around the world.
- Mavs center Dereck Lively II out at least a month with stress fracture in ankleby /u/Oldtimer_2 on January 23, 2025 at 1:25 am
submitted by /u/Oldtimer_2 [link] [comments]
- Mathieu Olivier et Ryan Reavesby /u/Western-Propaganda on January 23, 2025 at 12:57 am
submitted by /u/Western-Propaganda [link] [comments]
- Dodgers introduce prized Japanese pitcher Roki Sasaki, who gets $6.5 million signing bonusby /u/Oldtimer_2 on January 23, 2025 at 12:00 am
submitted by /u/Oldtimer_2 [link] [comments]
- Man City sent to brink of Champions League exit by PSG. Real Madrid routs Salzburg to advanceby /u/Oldtimer_2 on January 22, 2025 at 10:49 pm
submitted by /u/Oldtimer_2 [link] [comments]
- Heat planning to suspend Jimmy Butler for two games, sources sayby /u/PrincessBananas85 on January 22, 2025 at 10:40 pm
submitted by /u/PrincessBananas85 [link] [comments]